Restylane Refyne

Conveniently located to serve the areas of Tualatin and Portland, Oregon

Restylane Refyne

Restylane Refyne is an advanced hyaluronic acid (HA) filler formulation specifically designed to reduce the appearance of nasolabial folds and marionette lines. If you are considering dermal fillers to enhance your appearance, this injectable is a natural anti-aging solution that will leave your skin feeling and looking years younger. Restylane Refyne restores skin volume by reducing the depth of lines around your nose and mouth for a smoother appearance, helping you rediscover the beauty of your youth.

Gorin Plastic Surgery has helped thousands of patients preserve their youthful appearance and minimize wrinkles, and you can too. Although hyaluronic acid injections are not permanent, they are a long-lasting low-maintenance solution. Reducing the appearance of deep lines around the nose that develop with age is possible with this simple anti-aging injectable. In under an hour, we can eliminate decades of wrinkles and fine lines with a simple, effective treatment.

Contact our office or call (503)692-7222 to get started with booking your consultation and see what Restylane Refyne can do for you.

About Restylane Refyne

Restylane Refyne is primarily used to treat nasolabial folds, also known as smile lines or laugh lines. These lines extend from the side of the nose to the corners of the mouth and can become more pronounced with age. Aging can cause skin thickness to decrease and fat deposits to shift which can fundamentally change the shape of the face. (1) Facial skin becomes weaker, collagen production decreases, and gravity pulls tissues down, resulting in deeper lines between the nose and mouth. Smile lines can also result from exposure to the sun and environmental pollution.

If you are looking for a natural solution to signs of facial aging, you will love Restylane Refyne. With the help of the latest in dermal filler science, this treatment smooths facial lines so you can get your youthful contour back.

How is Restylane Refyne So Effective?

Restylane Refyne consists of moisture-attracting and cushioning HA, helping your skin achieve a softer, more vibrant appearance. It is also formulated with XpresHAn TechnologyTM. This advanced HA crosslinking technique allows Restylane Refyne to be a smooth, highly flexible, and soft gel that responds to facial expressions, for a natural-looking appearance.

Benefits of Restylane Refyne

With Restylane Refyne, you will see a noticeable reduction in facial lines for a rejuvenated, youthful look. The benefits of Restylane Refyne injections include the following:

  • Smoother, more youthful-looking skin: The hyaluronic acid gel fills in and smoothes out wrinkles and folds, resulting in a more even and youthful complexion.
  • Natural-looking results: Restylane Refyne provides subtle enhancements that maintain your facial expressions while minimizing the appearance of lines and wrinkles.
  • Long-lasting effects: The results of Restylane Refyne can last up to 12 months, allowing patients to enjoy their rejuvenated appearance for an extended period.
  • Minimally invasive: Restylane Refyne is a non-surgical treatment that requires minimal downtime, allowing you to return to your normal activities shortly after the procedure.
  • FDA-approved: Restylane Refyne has been approved by the FDA for the treatment of nasolabial folds and marionette lines, providing patients with confidence in its safety and efficacy.

Candidates for Restylane Refyne

If you are 21 years or older and need a soft tissue filler to enhance your natural facial contour, Restylane Refyne is an effective, low-maintenance solution.

Although the Restylane family of HA fillers is suitable for most people, there are some limitations. If you are allergic to lidocaine or gram-positive proteins, Restylane Refyne may not be suitable. Similarly, patients with bleeding disorders may not be the best candidates. If you are currently experiencing breakouts, sores, or rashes in the area where you wish to receive treatment, our team may recommend postponing your treatment until your skin recovers fully.

For patients who are experiencing severe facial wrinkles, Dr. Gorin will need to determine whether or not a more comprehensive treatment is required. Some severe types of folds, wrinkles, and volume loss may require alternative treatments. (2)

Personal Consultation

During your consultation, our team will discuss your medical history, expectations, and the results you wish to achieve with Restylane Refyne. We will also discuss the possibility of combining treatments and after-care precautions. We will also examine the area(s) you wish to enhance with Restylane Refyne. This evaluation will help determine if you are a suitable candidate for the procedure and allows us to recommend the most appropriate treatment plan to reach your beauty goals.

Preparation, Procedure, & Recovery

To prepare for Restylane injections, patients should:

  • Avoid blood thinners, supplements, and certain medications as instructed before the procedure.
  • Cease nicotine use in the weeks leading up to the treatment and throughout the recovery period.

Before the injection portion of treatment, we will thoroughly cleanse your skin. After this, we will use a small needle to inject Restylane Refyne beneath the skin in targeted areas of the face. The procedure takes an hour or less, depending on the number of areas you would like to treat.

After your injection, you can enjoy younger-looking skin without having to worry about smile lines. Recovery is minimal for Restylane Refyne, and you can return home immediately. (3) Some patients may experience discomfort, headaches, or swelling around the injection site, which will subside over time.


Restylane Refyne

After a Restylane Refyne injection, you can immediately enjoy plump, soft, hydrated skin. Since the injection is a flexible formula, you will notice a subtle enhancement and reduction of smile lines, and a filler that works seamlessly with your natural facial expressions. If you prefer a minimalistic approach, Restylane Refyne is the perfect low-maintenance anti-aging solution for a more youthful, radiant glow. The results of your Restylane Refyne injections will last for up to a year, after which, you can come in for maintenance treatments.

Corresponding Procedures

Restylane Lyft

Restylane Lyft is a dermal filler specifically designed for cheek hollowing. This is a denser formula that we will inject into the deeper layers of the skin to round out hollow cheeks and restore your youthful appearance.

Restylane Kysse

Restylane Kysse is an HA-based injection designed to increase the volume of your lips. The formula is created with XpresHAn technology; the formula contains smaller particles, allowing fluid and natural movement. If you would like to improve the appearance of your lips, we can discuss the best injection to help you achieve your desired look.


Like Restylane, the Juvéderm family of fillers is HA-based. Commonly treated areas include the nasolabial folds, marionette lines, and the lips. The longevity of Juvéderm results varies depending on several factors, such as the specific product used, individual patient characteristics, and lifestyle factors. In general, the effects of Juvederm fillers can last anywhere from several months to up to a year or longer.

To learn more about dermal fillers at Gorin Plastic Surgery, see our blog.

Cost of Restylane Refyne in Portland

The cost of your Restylane Refyne treatment will depend on the number of areas you would like to treat. At our Portland location, we have several specials and financing options for patients. Contact our office or call (503) 692-7222 to schedule a consultation and receive a quote for your treatment.


What if I am not a candidate for Restylane Refyne?

If you are not a candidate for Restylane Refyne, we will recommend an alternative treatment based on your goals and the results you are looking to achieve. During your initial consultation, we can discuss the best treatment to help you receive results.

If I start with Restylane can I get Juvéderm later?

Yes, we can even use both injections during your appointment for a customized procedure. Dermal fillers are so customizable, which is one of the many reasons we love them. Depending on your consultation, you may wish to receive both injections for the best results.

What if I am not happy with the results of Restylane Refyne?

Although most patients love the results of injections, if you would like to adjust your results we will work with you to achieve your desired look. During your initial consultation, we will discuss your expectations in-depth and create a plan to suit your needs.

Will people be able to tell that I had dermal fillers?

No, our team is extremely skilled at what we do. Your injection will help you achieve a natural look and feel. We will carefully evaluate your individual facial anatomy and aesthetic goals to ensure that the injectable gel is placed accurately, achieving balanced and harmonious results.


  1. Hur M, O. J, Yang H, et al. Heights and spatial relationships of the facial muscles acting on the nasolabial fold by dissection and three-dimensional microcomputed tomography. Molnar J, ed. PLOS ONE. 2020;15(8):e0237043. doi:
  2. Mohammad Ali Nilforoushzadeh, Heidari‐Kharaji M, Tannaz Fakhim, et al. Efficacy evaluation of endolift laser for treatment of nasolabial folds and marionette lines. Skin research and technology. 2023;29(10). doi:
  3. Swift A, von Grote E, Jonas B, Nogueira A. Minimal recovery time needed to return to social engagement following nasolabial fold correction with hyaluronic acid fillers produced with XpresHAn technology. Clinical, Cosmetic and Investigational Dermatology. 2017;10:229-238. doi: